Steven R Grossman Selected Research

C-terminal binding protein

1/2020	CtBP determines ovarian cancer cell fate through repression of death receptors.
8/2018	An intestinal stem cell niche in Apc mutated neoplasia targetable by CtBP inhibition.
1/2014	Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells.
9/2010	Therapeutic targeting of C-terminal binding protein in human cancer.
1/2008	p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Steven R Grossman Research Topics

Disease

28	Neoplasms (Cancer) 01/2021 - 01/2002
7	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2008
5	Carcinogenesis 01/2021 - 10/2010
4	Lung Neoplasms (Lung Cancer) 01/2020 - 07/2012
4	Colonic Neoplasms (Colon Cancer) 01/2014 - 03/2006
2	Hypoxia (Hypoxemia) 01/2021 - 10/2007
2	Adenocarcinoma 01/2021 - 07/2013
2	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 01/2019
2	Tics (Tic) 10/2019 - 08/2018
2	Intestinal Polyposis (Polyposis, Intestinal) 01/2019 - 08/2018
2	Breast Neoplasms (Breast Cancer) 01/2019 - 10/2007
2	Pancreatic Neoplasms (Pancreatic Cancer) 11/2014 - 01/2002
2	Carcinoma (Carcinomatosis) 07/2012 - 10/2007
1	COVID-19 11/2021
1	Acute Lung Injury 11/2021
1	Infections 11/2021
1	Ovarian Epithelial Carcinoma 01/2020
1	Starvation 12/2019
1	Rectal Neoplasms (Rectal Cancer) 10/2019
1	Polyps 01/2019
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 08/2018
1	Adenoma (Adenomas) 08/2018
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2018
1	Ataxia (Dyssynergia) 01/2016
1	Colorectal Neoplasms (Colorectal Cancer) 07/2015
1	Peritoneal Neoplasms 07/2015
1	Lymphoma (Lymphomas) 01/2014
1	T-Cell Lymphoma (Lymphoma, T Cell) 07/2012
1	Hepatocellular Carcinoma (Hepatoma) 01/2008
1	Febrile Neutropenia 01/2002

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2006
5	Carrier Proteins (Binding Protein)IBA 01/2021 - 10/2007
5	C-terminal binding proteinIBA 01/2020 - 01/2008
5	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 09/2010
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 10/2010
3	Gemcitabine FDA Link 10/2019 - 01/2002
3	Tumor Suppressor Protein p14ARF (p14ARF)IBA 07/2015 - 06/2004
3	Co-Repressor ProteinsIBA 07/2012 - 10/2007
2	Biological ProductsIBA 11/2021 - 07/2011
2	NAD (NADH)IBA 01/2021 - 01/2014
2	RNA (Ribonucleic Acid)IBA 01/2020 - 07/2012
2	phenylpyruvic acidIBA 10/2019 - 08/2018
2	Fluorouracil (Carac)FDA LinkGeneric 10/2019 - 07/2013
2	TransferasesIBA 01/2017 - 01/2014
2	Histones (Histone)IBA 01/2017 - 01/2014
2	UbiquitinIBA 01/2016 - 10/2010
2	Small Interfering RNA (siRNA)IBA 10/2007 - 03/2006
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	cediranib (AZD2171)IBA 01/2021
1	Amino Acids FDA Link 01/2021
1	olaparibIBA 01/2021
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2021
1	Death Domain ReceptorsIBA 01/2020
1	Proteasome InhibitorsIBA 01/2020
1	guanidine thiocyanate (guanidinium thiocyanate)IBA 01/2020
1	Chloroform (Trichloromethane)IBA 01/2020
1	NitrogenIBA 01/2020
1	Ribonucleases (Ribonuclease)IBA 01/2020
1	Mechanistic Target of Rapamycin Complex 1IBA 12/2019
1	Mechanistic Target of Rapamycin Complex 2IBA 12/2019
1	SestrinsIBA 12/2019
1	Glucose (Dextrose)FDA LinkGeneric 12/2019
1	Phosphotransferases (Kinase)IBA 12/2019
1	Tumor Suppressor Protein p53IBA 12/2019
1	Sirolimus (Rapamycin)FDA Link 12/2019
1	2-hydroxyimino-3-phenylpropanoic acidIBA 01/2019
1	Oncogene Proteins (Oncogene Protein)IBA 01/2017
1	ErbB Receptors (EGF Receptor)IBA 03/2016
1	ChromatinIBA 03/2016
1	MutagensIBA 01/2016
1	Serine (L-Serine)FDA Link 01/2016
1	Poly CIBA 11/2014
1	Lysine (L-Lysine)FDA Link 01/2014
1	Transcription Factor 4IBA 01/2014
1	Cetuximab (Erbitux)FDA Link 07/2013
1	Messenger RNA (mRNA)IBA 07/2012
1	T-Lymphoma Invasion and Metastasis-inducing Protein 1IBA 07/2012
1	GTP Phosphohydrolases (GTPases)IBA 07/2012
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 07/2012
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 07/2012
1	Transcription Factors (Transcription Factor)IBA 03/2012
1	LuciferasesIBA 07/2011
1	Pharmaceutical PreparationsIBA 10/2010
1	EnzymesIBA 10/2010
1	Ligases (Synthetase)IBA 10/2010
1	Deubiquitinating EnzymesIBA 10/2010
1	2-keto-4-methylthiobutyric acidIBA 09/2010
1	Enterotoxin ReceptorsIBA 06/2010
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2008
1	AgarIBA 01/2008
1	Indicators and Reagents (Reagents)IBA 10/2007
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 10/2007
1	Tyrosine (L-Tyrosine)FDA Link 10/2007
1	Docetaxel (Taxotere)FDA Link 01/2002

Therapy/Procedure

9	Therapeutics 01/2021 - 10/2007
3	Drug Therapy (Chemotherapy) 01/2021 - 01/2002
2	Radiotherapy 10/2019 - 07/2013
1	Precision Medicine 01/2018
1	Injections 07/2011
1	Drug Tapering 01/2002